BioScience Dictionary

 
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Found Alkaline phosphatase 2 times.

Displaying results 1 to 10.

1. Alkaline phosphatase
An enzyme which hydrolyzes phosphate ester s and works best in the pH range of 9 to 11; it catalyzes the removal of phospate groups near the 5' end of linear DNA strands such as restricted plasmid molecules. This enzyme is typically obtained from calf intestinal tissue or E. coli and is used widely in gene cloning experiments and in enzyme-antibody conjugates in ELISA and immunochemistry .

2. Alkaline phosphatase (ALP)
This is an enzyme that is produced by liver cells lining the collecting system (Kupffer's cells). Its level is elevated in conditions of obstruction of biliary collecting system (such as by cancer and gallstones), cirrhosis of liver and bone growth, infarcting bowel, and metastatic tumor to bone. (Normal range: 50-190 IU/L; in children it can be up to 300 IU/L)