BioScience Dictionary

 
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Found DNase I 3 times.

Displaying results 1 to 10.

1. DNase I
A type of endonuclease , or enzyme that breaks down DNA molecules at their phosphodiester bond s. It is found in large quantities in the pancreas.

2. DNase I hypersensitivity site (DNase I hypersensitive site)
A site on a DNA molecule that is especially prone to being cut apart by the endonuclease enzyme DNase I , which breaks down DNA into smaller fragments by cleaving phosphodiester bond s. These sites tend to be near active gene s, which are regularly transcribed.

3. DNase I sensitivity
The likelihood that a particular DNA segment will be attacked by the endonuclease enzyme DNase I , which breaks down DNA into smaller fragments by cleaving its phosphodiester bond s. DNA segments which contain active gene s that are regularly transcribed are more prone to being cut apart by DNase I than inactivated genes, because the inactivated genes are generally within condensed regions of the chromosome , while the active genes are in more open configurations for easy access for transcription.

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