BioScience Dictionary

 
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Found DNase I sensitivity 1 time.

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1. DNase I sensitivity
The likelihood that a particular DNA segment will be attacked by the endonuclease enzyme DNase I , which breaks down DNA into smaller fragments by cleaving its phosphodiester bond s. DNA segments which contain active gene s that are regularly transcribed are more prone to being cut apart by DNase I than inactivated genes, because the inactivated genes are generally within condensed regions of the chromosome , while the active genes are in more open configurations for easy access for transcription.