BioScience Dictionary

 
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Found Autoimmune 13 times.

Displaying results 1 to 10.

1. Anti-nuclear antibody
Anti-nuclear antibody (ANA) is an antibody against nuclear materials such as DNA , RNA , histone or non-histone protein s. ANA is usually found in the serum of individuals with certain autoimmune diseases, e.g., systemic lupus erythematosus (SLE), Sjogren's syndrome, polymyositis, systemic sclerosis, etc. Different diseases have ANA against different nuclear components.

2. Autoantibody (pl. autoantibodies)
An antibody involved in autoimmune reactions.

3. Autoimmune
A condition where the body's immune system is unable to distinguish between foreign particles and the body's own cells and as a result attacks normal body tissue.

4. Autoimmune disease
Disorder of the body's immune system in which the immune system mistakenly attacks and destroys body tissue that it believes to be foreign. insulin -dependent diabetes is an autoimmune disease because the immune system attacks and destroys the insulin-producing beta cell s.

5. Biliary cirrhosis
A chronic disease of the liver characterized by the autoimmune destruction of the organ. Patients affected are usually women from 40-60 years of age.

6. Clonal deletion
The removal of B cell and T cell varieties which recognize parts of the organism's body as targets of the immune system . This process naturally occurs early in the organism's development so that the organism will not be autoimmune (having an immune reaction against one's own body tissues) later in life.

7. Eaton-Lambert syndrome (Lambert-Eaton syndrome, myasthenic syndrome)
Eaton-Lambert syndrome is characterized by weakness of the proximal muscles of the limbs, often associated with small cell carcinoma (of the lung) and some autoimmune diseases. This condition is caused by the body creating antibodies against its own motor nerve axon terminals.

8. Freund's adjuvant
The complete version of this immunostimulating adjuvant contains heat-killed tuberculosis bacteria emulsified in white mineral oil. It is used in immunological research involving lab animals, but not in humans, since it could cause allergic responses or autoimmune problems. The bacterial cells are omitted in the incomplete verson of the adjuvant.

9. Idiopathic thrombocytopenic purpura (ITP)
Idiopathic thrombocytopenic purpura is an autoimmune disorder involving the creation of IgG autoantibodies against blood platelet s.

10. Multiple sclerosis (MS)
In this autoimmune disease, the body attacks its own nervous system, destroying the myelin sheath that protects the nerve cells. This prevents the nerves from carrying signals properly, and afflicted persons can experience problems with muscular coordination, vision and other sensory problems, and paralysis. The root cause of the disease is unknown; many scientists believe an as-yet-unidentified virus or virion may be the culprit, but recent research points strongly to a genetic factor as well.


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