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Found Endonuclease 12 times.

Displaying results 1 to 10.

1. DNase footprinting
A lab technique used to find out which segments of a DNA molecule are protected by DNA-binding protein s from attack by endonuclease enzyme s, which break down DNA into smaller fragments by cleaving its phosphodiester bond s. The technique does this with gel electrophoresis to find out which parts of the DNA have sites for proteins to attach to them, by comparing DNA which has been in the presence of DNA-binding proteins with DNA that is "pure."

2. DNase I
A type of endonuclease , or enzyme that breaks down DNA molecules at their phosphodiester bond s. It is found in large quantities in the pancreas.

3. DNase I hypersensitivity site (DNase I hypersensitive site)
A site on a DNA molecule that is especially prone to being cut apart by the endonuclease enzyme DNase I , which breaks down DNA into smaller fragments by cleaving phosphodiester bond s. These sites tend to be near active gene s, which are regularly transcribed.

4. DNase I sensitivity
The likelihood that a particular DNA segment will be attacked by the endonuclease enzyme DNase I , which breaks down DNA into smaller fragments by cleaving its phosphodiester bond s. DNA segments which contain active gene s that are regularly transcribed are more prone to being cut apart by DNase I than inactivated genes, because the inactivated genes are generally within condensed regions of the chromosome , while the active genes are in more open configurations for easy access for transcription.

5. Endonuclease
An enzyme that cleaves its nucleic acid substrate at internal sites (the phosphodiester bonds) in the nucleotide sequence.

6. Endonuclease S1
A nuclease enzyme from the fungus Aspergillus oryzae which cuts the phosphodiester bond s between nucleotide s in single-stranded DNA or RNA , producing individual nucleotide molecules.

7. Hypersensitive site (hypersensitivity site)
A short segment of DNA which is especially prone to being cleaved by endonuclease enzyme s like DNase . These sites tend to be within gene promoter regions.

8. Isoschisomer (isoschizomer, isoschisomere, isoschizomere)
One of several restriction endonuclease s which are isolated from different sources but which break a DNA molecule at the same recognition site.

9. Linker
A short, double-stranded oligonucleotide containing a restriction endonuclease recognition site, which is ligated to the ends of a DNA fragment.

10. Recognition sequence (recognition site)
A nucleotide sequence -- typically composed of 4, 6, or 8 nucleotides -- that is recognized by a restriction endonuclease . Type II enzyme s cut (and their corresponding modification enzymes methylate) within or very near the recognition sequence.


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