BioScience Dictionary

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Ot.

Found Frameshift 3 times.

Displaying results 1 to 10.

1. Acridine orange
3,6-bis(dimethylamino)acridinium chloride. A toxic, fluorescing dye that stains DNA and RNA and is typically used to identify cancerous tumor cells. When it binds to double-stranded DNA , it fluoresces green; when it binds with the phosphate groups of single-stranded DNA or RNA , it fluoresces orange. The chemical also causes frameshift mutations.

2. Chromosomal mutation
Can refer to any of a number of DNA mutation s which results in a change in the protein encoded by the mutated gene , such as point mutation s, insertion or deletion mutation s ( frameshift mutation s), or nonsense mutation s. More often this refers to mutations involving chromosome s, such as the inversion of part of one chromosome such that the inverted part no longer matches with its homologous pair , a translocation of one part of a chromosome to a different chromosome, deletions of parts of chromosomes, or accidents which happen during the division of the nucleus like the unequal portioning of chromosomes between the daughter cells.

3. Frameshift mutation (frame shift mutation, frame-shift mutation)
A type of mutation in which one or more paired nucleotide s are inserted or deleted in the coding region of a gene , which causes the triplet codon s to be read in the wrong frame; the resulting polypeptide has a garbled amino acid sequence from the mutated codon on.

View web definitions »

Learn more about Frameshift »