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Found Host 113 times.

Displaying results 1 to 10.

1. 3'-azido-3'-deoxythymidine (AZT)
An antibiotic used to treat infection by HIV (the AIDS virus ). The drug works by blocking replication of the HIV genetic material (in this case it is composed of RNA rather than DNA ) by preventing the viral RNA from inserting into the host DNA.

2. Adherence
Refers to the ability of bacteria adhere (stick) to host surfaces.

3. African sleeping sickness
A disease affecting humans and other mammals in central Africa that is caused by the parasitic protozoa ns Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense and is transmitted by the tsetse fly. Symptoms include fever, chills, headache, vomiting, pain in the extremities, lymph gland enlargement, anemia, depression, fatigue, coma, and eventually death if left untreated. The trypanosome is able to evade the host's immune system by frequently changing the protein s on its outer surface, by which the immune system identifies intruders.

4. Aggressin
A term for a protein produced by a pathogenic microbe which aids its spread in the host by inhibiting the host's immune system (specifically the response by phagocyte s).

5. Antigenic switching
The process by which a pathogenic microbe's genetic structure is altered to change its surface antigen s in order to avoid being detected by the host 's immune system.

6. Antigenic variation
A change in the structure of an antigen on the surface of a disease-causing microorganism or virus (a pathogen ) so that the host's immune system no longer recognizes the pathogen and must make new antibodies to recognize the changed antigens before the host can continue to combat the disease. As a result, the host cannot stay immune to the disease.

7. Arrayed library
Individual primary recombinant clone s (hosted in phage , cosmid , YAC , or other vector ) that are placed in two-dimensional arrays in microtiter dishes. Each primary clone can be identified by the identity of the plate and the clone location (row and column) on that plate. Arrayed libraries of clones can be used for many applications, including screening for a specific gene or genomic region of interest as well as for physical mapping . Information gathered on individual clones from various genetic linkage and physical map analyses is entered into a relational database and used to construct physical and genetic linkage map s simultaneously; clone identifiers serve to interrelate the multilevel maps. Compare library , genomic library .

8. Autoecious
Term used to describe a parasite that uses only one host for its lifecycle. Compare heteroecious .

9. Bacteriotropin
Something which combines with bacteria , such as an antibody , so that the bacteria becomes more likely to get destroyed by its host's immune system .

10. Baltimore, David
Born 1938. An American molecular biologist and virologist who won the Nobel Prize in 1975 for discovering that retrovirus es (a group of virus es that uses RNA to code their genome s instead of DNA ) make the enzyme " reverse transcriptase ," which is used to make DNA copies of RNA templates. This is useful to the retrovirus who is trying to reproduce with host cellular machinery. More important, this is very useful to molecular biologists and genetic engineer s who want to work with RNA molecules using DNA-manipulating techniques.

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