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Found Inherit 92 times.

Displaying results 1 to 10.

1. Abnormal hemoglobin
Hemoglobin molecule with a different shape due to an altered amino acid sequence (ultimately caused by an altered DNA base sequence), such as in the inherited disease sickle-cell anemia .

2. Adenosine deaminase deficiency (ADA)
inherited disorder caused by insufficient adenosine deaminase activity, resulting in a compromised immune system .

3. Agammaglobulinemia (adj.: agammaglobulinemic)
A rare disease where the body is unable to produce immune antibodies due to the lack of gamma globulin , a type of immunoglobulin , in the blood. The disease can be acquired or inherited as an X-linked recessive genetic disease.

4. Albinism
A rare genetic condition in which the body has no pigment whatsoever, due to an inherited inability to correctly manufacture melanin. This means that the animal with the condition (called an albino ) has white, pale pink, or even translucent skin, white fur or hair, and pink eyes (no pigment in the iris means that the only color comes from the blood vessels in the eye).

5. Alleles
Alternative forms of a genetic locus; a single allele for each locus is inherited separately from each parent (e.g., at a locus for eye color the allele might result in blue or brown eyes).

6. Alpha thalassemia
One of two major types of thalassemia , a genetically inherited disease, in which one of the two types of polypeptide s making up the hemoglobin protein is defective or missing. Hemoglobin proteins are composed of four polypeptides -- two "alpha chains" and two "beta chains". In alpha thalassemia, the alpha chains are defective or missing (see also beta thalassemia ). This disease mainly affects individuals of Southeast Asian, Chinese, and Filipino ancestry; in its most severe form it results in the death of the fetus or newborn. Individuals with less severe cases have varying degrees of anemia .

7. Alport's syndrome (Alport syndrome)
Alport's syndrome consists of progressive nephritis , nerve deafness, leading to kidney failure in the second to third decades of life. Autosomal dominant, autosomal recessive, and X-linked inheritance are noted.

8. Anti-phospholipid syndrome
Anti-phospholipid syndrome is an autosomally inherited genetic disorder in which an affected individual produces antibodies against his/her own cellular phospholipid components. This is manifested clinically as a tendency to have arterial and venous thrombosis , thrombocytopenia and recurrent fetal loss (miscarriage).

9. Autosomal dominant (autosomal dominance)
This is a type of genetic inheritance ; a person who carries the gene on one allele will express (experience effects from) that gene. An autosomal dominant gene can be inherited from a single affected parent; both sons and daughters have an equal chance of inheriting the gene.

10. Autosomal recessive
An autosomal recessive gene is one which is required in two copies on an autosome to be active in an organism. For instance, a person who carry two copies of the same abnormal gene (in other words, this person is homozygous for the gene) will experience effects from that gene (for instance, he or she might then suffer from a disease coded by that gene). The gene can be inherit ed from both parents who carry the gene; sons and daughters have an equal chance of inheriting the gene. If a person has a genetic disease but his or her parents seem normal, then this probably means that: * The parents of this person are heterozygous , unaffected carriers of the disease, or * The person inherited one copy of the gene from a parent, and the other "good" copy underwent a mutation early in the person's embryonic development


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