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Found Metabolite 17 times.

Displaying results 1 to 10.

1. Activator
In biochemistry: * A DNA -binding protein that regulates one or more gene s by increasing the rate of transcription . * A metabolite that positively modulates an allosteric enzyme .

2. Allosteric enzyme
A regulatory enzyme whose activity is modified by the noncovalent binding of a particular metabolite at a site (the allosteric site) other than the active site.

3. Amphibolic
A metabolic pathway that can both create and destroy metabolite s (that is, it is both anabolic and catabolic ). Such an intermediate pathway allows using the breakdown products from one pathway as the substrate s, or ingredients, for a compound in another pathway.

4. Anti-metabolite
An analog of the end-product of a metabolic pathway that causes feedback inhibition or repression , but cannot replace the genuine product; used for selecting feedback-deficient mutant s.

5. Aptamer (adaptamer)
A type of synthetic oligonucleotide that can bind to a particular target molecule, such as a protein or metabolite .

6. Biological monitoring
This is the periodic examination of biological specimens for the purposes of monitoring their exposure to or the effects of potentially toxic chemicals to the environment. This is normally done by analyzing the amounts of the toxic substances or their metabolites present in body tissues and fluids. The term is also used to mean assessment of the biological status of populations and communities of organisms at risk, in order to protect them and to gain an early warning of possible hazards to human health.

7. Clinical chemistry
This is the use of laboratory chemistry techniques to aid in the diagnosis or treatment of diseases and disorders. Clinical chemistry techniques can involve such things as testing blood or urine for the presence of certain biomolecules or metabolites, therapeutic drug monitoring, etc. See also immunology , hematology , toxicology , nutrition , and endocrinology .

8. Fluorouracil
A chemical used in chemotherapy to treat mainly breast, skin and gastrointestinal cancers. It prevents the growth and spread of cancer cells (it is both an antineoplast ic and an antimetabolite).

9. Hemodialysis
Hemodialysis is performed by extracorporeal circulation of the patient's blood such that the dialysate solution and the blood is separated only by a thin membrane which allows water soluble molecules to exchange. Since the dialysate contains low concentration of many of the toxic metabolite s and potassium , this method effectively lowers the concentration such molecules in blood.

10. Inborn errors of metabolism
Inborn errors of metabolism are genetic disorders due to single gene defects. Many inborn errors of metabolism are abnormalities of enzyme s in metabolic pathways. Because this, intermediate metabolites accumulate. Some of the most well known inborn errors of metabolism are: phenylketonurea , Lesch-Nyhan Syndrome , Gaucher's disease and the glycogen storage disease s.


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