BioScience Dictionary

 
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Ot.

Found Trypanosome 6 times.

Displaying results 1 to 10.

1. African sleeping sickness
A disease affecting humans and other mammals in central Africa that is caused by the parasitic protozoa ns Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense and is transmitted by the tsetse fly. Symptoms include fever, chills, headache, vomiting, pain in the extremities, lymph gland enlargement, anemia, depression, fatigue, coma, and eventually death if left untreated. The trypanosome is able to evade the host's immune system by frequently changing the protein s on its outer surface, by which the immune system identifies intruders.

2. Expression site
The location in the genome of the gene for the "variable surface glycoprotein " that is currently being expressed (an expression-linked copy ) by the trypanosome (a parasitic protozoan which causes the disease African sleeping sickness ). Most of these sites are near the ends, or telomere s, of a chromosome .

3. Expression-linked copy (ELC)
One of many different versions of the "variable surface glycoprotein gene " of the trypanosome (a parasitic protozoan which causes the disease African sleeping sickness ); refers to whichever one of them is currently being expressed on the outer surface of the trypanosome.

4. Leishmania
A genus of parasitic flagellated protozoan s which causes diseases in animals including humans, most notably leishmaniasis . A type of trypanosome .

5. Trypanosome
A type of parasitic protozoan which can cause a number of serious diseases in people and domestic animals, including African sleeping sickness and leishmaniasis . The trypanosome is able to remain within a host 's body for a very long time because it regularly changes the protein s (i.e. antigen s) on its outer surface, so that the host's immune system must constantly develop new antibodies in order to continue to recognize and destroy it. The trypanosome uses a large number of different gene s which can be used in many combinations to come up with the different surface proteins. As a result, the host is never able to completely eliminate the trypanosome.

6. Trypanosomes
A type of roundworm, responsible for human disease associated with eating raw or undercooked pork.

View web definitions »

Learn more about Trypanosome »