Keratin 9

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KRT9
Identifiers
AliasesKRT9, CK-9, EPPK, K9, keratin 9
External IDsOMIM: 607606 HomoloGene: 133554 GeneCards: KRT9
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for KRT9
Genomic location for KRT9
Band17q21.2Start41,565,836 bp[1]
End41,572,059 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000226

n/a

RefSeq (protein)

NP_000217

n/a

Location (UCSC)Chr 17: 41.57 – 41.57 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Keratin 9 is a protein that in humans is encoded by the KRT9 gene.[3][4]

Keratin 9 is a type I cytokeratin. It is found only in the terminally differentiated epidermis of palms and soles. Mutations in the gene encoding this protein cause epidermolytic palmoplantar keratoderma.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171403 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Langbein L, Heid HW, Moll I, Franke WW (December 1993). "Molecular characterization of the body site-specific human epidermal cytokeratin 9: cDNA cloning, amino acid sequence, and tissue specificity of gene expression". Differentiation. 55 (1): 57–71. doi:10.1111/j.1432-0436.1993.tb00033.x. PMID 7507869.
  4. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
  5. ^ Reis A, Hennies HC, Langbein L, Digweed M, Mischke D, Drechsler M, Schröck E, Royer-Pokora B, Franke WW, Sperling K (February 1994). "Keratin 9 gene mutations in epidermolytic palmoplantar keratoderma (EPPK)". Nat. Genet. 6 (2): 174–9. doi:10.1038/ng0294-174. PMID 7512862.

Further reading