|Systematic IUPAC name
|Molar mass||81.1158 g mol−1|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is: / ?)(|
Dihydropyridine is a molecule based upon pyridine, and the parent of a class of molecules that have been semi-saturated with two substituents replacing one double bond. They are particularly well known in pharmacology as L-type calcium channel blockers, used in the treatment of hypertension. Compared with certain other L-type calcium channel blockers (for example those of the phenylalkylamine class such as verapamil) which have significant action at the heart, they are relatively vascular selective in their mechanism of action in lowering blood pressure.
The L-type calcium channel blockers include, in alphabetical order (brand names vary in different countries): These are derivatives of dihydropyridine.
|Amlodipine||Norvasc, Istin, Normodipine, Tenox, Cordi Cor|
|Barnidipine||Vasexten, Libradin, Cyress, HypoCa|
|Cilnidipine||Atelec (アテレック), Cilacar, Cinalong, Siscard|
|Lacidipine||Lacipil, Motens, Sakure|
|Manidipine||Manyper, Caslot, Madipine|
|Nicardipine||Cardene, Cardene SR|
|Nifedipine||Adalat, Nifedical, Procardia, Corinfar, Cordaflex|
|Nisoldipine||Sular, Baymycard, Syscor|
|Nitrendipine||Baypress, Cardif, Nitrepin, Baylotensin|
- "1,4-dihydropyridine - Compound Summary". Pubchem Compound. USA: National Center for Biotechnology Information. 27 March 2005. Identification and Related Records. Retrieved 1 November 2011.
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