Macromerine - Wikipedia, the free encyclopedia
Macromerine
From Wikipedia, the free encyclopedia
Macromerine
1-(3,4-dimethoxyphenyl)-2-(dimethylamino)ethanol
Identifiers
CAS number 2970-95-8
PubChem 165055
ChemSpider 144706 Y
Jmol -3D imagesImage 1
O(c1ccc(cc1OC)C(O)CN(C)C)C
InChI=1S/C12H19NO3/c1-13(2)8-10(14)9-5-6-11(15-3)12(7-9)16-4/h5-7,10,14H,8H2,1-4H3 Y Y
InChI=1/C12H19NO3/c1-13(2)8-10(14)9-5-6-11(15-3)12(7-9)16-4/h5-7,10,14H,8H2,1-4H3
Properties
Molecular formula C12 H19 NO3
Molar mass 225.284 g/mol
Y (verify) (what is: Y /N ?)standard state (at 25 °C, 100 kPa)
Infobox references
Macromerine is a psychoactive phenethylamine . It can be synthesized or extracted from the Doñana (Coryphantha macromerisC. macromeris v. runyonii , C. elephantidens , and other related members of the Cactaceae family. The plants may have been used by Tarahumara shamans for their entheogenic effects.
Chemistry Macromerine is in a family of chemicals called the phenethylamines, and it is a close analogue of mescaline . The full chemical name of macromerine is 1-(3,4-dimethoxyphenyl)-2-(dimethylamino)ethanol.
Dosage Macromerine is said to have "1/5" the potency of mescaline, so a dosage could be 1250-2500 mg based on the dosage of mescaline sulfate .
Effects Little is known about the psychedelic effects of macromerine. K. Trout states that a bioassay of macromerine-containing cactus, Doñana, "had been very mild and very strange, with many waves of intense nausea and extremely persistent after effects, such as distorted vision and a very weird feeling of unreality lasting for weeks after its use."
However, considering Doñana is usually no more than 0.1 percent macromerine, several pounds of the dried cactus would be required to consume a psychedelic dosage of macromerine. What is more likely is that the combination of all alkaloids present in the cactus produce the effects of Doñana.
Legality Macromerine is not illegal in any known part of the world.
External links
Psychedelics 5-HT2A R agonists
Lysergamides :AL-LAD ALD-52 BU-LAD CYP-LAD DAM-57 Diallyllysergamide Ergometrine ETH-LAD LAE-32 LSA LSD LSH LPD-824 LSM-775 Lysergic acid 2-butyl amide Lysergic acid 2,4-dimethylazetidide Lysergic acid 3-pentyl amide Methylergometrine Methylisopropyllysergamide Methysergide MLD-41 PARGY-LAD PRO-LAD Phenethylamines :Aleph 2C-B 2C-B-Dragonfly 2C-B-FLY 2C-C-FLY 2C-D-FLY 2C-E-FLY 2C-I-FLY 2CBFly-NBOMe 2C-T-7-FLY 2C-C 2C-C-NBOMe 2C-CN-NBOMe 2C-D 2CD-5EtO 2C-D-NBOMe 2C-E 2C-EF 2C-E-NBOMe 2C-F 2C-F-NBOMe 2C-G 2C-G-NBOMe 2C-H-NBOMe 2C-I 2C-N 2C-N-NBOMe 2C-O 2C-O-4 2C-P 2C-T 2C-T-2 2C-T-4 2C-T-4-NBOMe 2C-T-7 2C-T-7-NBOH 2C-T-8 2C-T-9 2C-T-13 2C-T-15 2C-T-17 2C-T-21 2C-TFM 2C-TFM-NBOMe 2C-YN 2CBCB-NBOMe 25B-NBOMe 25I-NBMD 25I-NBOH 25I-NBOMe 3C-AL 3C-E 3C-P 5-APB 5-APDB 6-APB 6-APDB Br-DFLY DESOXY DMMDA DMMDA-2 DOB DOB-FLY DOM-FLY DOC DOEF DOET DOF DOI DOM DON DOPR DOTFM Escaline Ganesha HOT-2 HOT-7 HOT-17 IAP Isoproscaline Jimscaline Lophophine MDA MDEA MDMA MMA MMDA MMDA-2 MMDA-3a MMDMA Macromerine Mescaline Methallylescaline NBOMe-mescaline Proscaline TCB-2 TFMFly TMA Piperazines :pFPP TMFPP Tryptamines :1-Methyl-5-methoxy-diisopropyltryptamine 2,N,N-TMT 4,N,N-TMT 4-HO-5-MeO-DMT 4-Acetoxy-DET 4-Acetoxy-DIPT 4-Acetoxy-DMT 4-Acetoxy-DPT 4-Acetoxy-MiPT 4-HO-DPT 4-HO-MET 4-Propionyloxy-DMT 4-HO-MPMI 5-Me-MIPT 5-N ,N -TMT 5-AcO-DMT 5-MeO-2,N ,N -TMT 5-MeO-4,N ,N -TMT 5-MeO-α,N,N-TMT 5-MeO-α-ET 5-MeO-α-MT 5-MeO-DALT 5-MeO-DET 5-MeO-DIPT 5-MeO-DMT 5-MeO-DPT 5-MeO-EiPT 5-MeO-MET 5-MeO-MIPT 5-MeO-MPMI 7,N,N-TMT α,N,N-TMT α-ET α-MT AL-37350A Baeocystin Bufotenin DALT DBT DCPT DET DIPT DMT DPT EiPT Ethocin Ethocybin Iprocin MET Miprocin MIPT Norbaeocystin PiPT Psilocin Psilocybin Others: AL-38022A Elemicin Ibogaine Myristicin Noribogaine Voacangine
Dissociatives NMDAR antagonists
Deliriants mAChR antagonists
Miscellaneous
Agonists : Azapirones : Alnespirone Binospirone Buspirone Enilospirone Eptapirone Gepirone Ipsapirone Perospirone Revospirone Tandospirone Tiospirone Umespirone Zalospirone ; Antidepressants : Etoperidone Nefazodone Trazodone Vortioxetine ; Antipsychotics : Aripiprazole Asenapine Clozapine Quetiapine Ziprasidone ; Ergolines : Dihydroergotamine Bromocriptine Ergotamine Lisuride Methysergide LSD ; Tryptamines : 5-CT 5-MeO-DMT 5-MT Bufotenin DMT Indorenate Psilocin Psilocybin ; Others : 8-OH-DPAT Adatanserin Bay R 1531 Befiradol BMY-14802 Cannabidiol Dimemebfe Ebalzotan Eltoprazine F-11,461 F-12,826 F-13,714 F-14,679 F-15,063 F-15,599 Flesinoxan Flibanserin Lesopitron LY-293,284 LY-301,317 MKC-242 Naluzotan NBUMP Osemozotan Oxaflozane Pardoprunox Piclozotan Rauwolscine Repinotan Roxindole RU-24,969 S 14,506 S-14,671 S-15,535 Sarizotan SSR-181,507 Sunepitron U-92,016-A Urapidil Vilazodone Xaliproden Yohimbine Antagonists : Antipsychotics : Iloperidone Risperidone Sertindole ; Beta blockers : Alprenolol Cyanopindolol Iodocyanopindolol Oxprenolol Pindobind Pindolol Propranolol Tertatolol ; Others : AV965 BMY-7,378 CSP-2503 Dotarizine Flopropione GR-46611 Isamoltane Lecozotan Mefway Metitepine/Methiothepin MPPF NAN-190 Robalzotan S-15535 SB-649,915 SDZ 216-525 Spiperone Spiramide Spiroxatrine UH-301 WAY-100,135 WAY-100,635 Xylamidine
Agonists : Lysergamides : Dihydroergotamine Methysergide ; Triptans : Almotriptan Avitriptan Eletriptan Frovatriptan Naratriptan Rizatriptan Sumatriptan Zolmitriptan ; Tryptamines : 5-CT 5-Ethyl-DMT 5-MT 5-(Nonyloxy)tryptamine ; Others : CP-135,807 Bromocriptine CP-286,601 GR-46611 L-694,247 L-772,405 PNU-109,291 PNU-142633 Antagonists : Lysergamides : Metergoline ; Others : Alniditan BRL-15,572 Elzasonan GR-127,935 Ketanserin LY-310,762 LY-367,642 LY-456,219 LY-456,220 Metitepine/Methiothepin Ritanserin Yohimbine Ziprasidone
Agonists : Phenethylamines : 2C-B 2C-E 2C-I 2C-T-2 2C-T-7 2C-T-21 DOB DOC DOI DOM MDA MDMA Mescaline ; Piperazines : Aripiprazole mCPP TFMPP ; Tryptamines : 5-CT 5-MeO-α-ET 5-MeO-α-MT 5-MeO-DET 5-MeO-DiPT 5-MeO-DMT 5-MeO-DPT 5-MT α-ET α-Methyl-5-HT α-MT Bufotenin DET DiPT DMT DPT Psilocin Psilocybin ; Others : A-372,159 Bromocriptine AL-38022A CP-809,101 Dimemebfe Lorcaserin Medifoxamine MK-212 Org 12,962 ORG-37,684 Oxaflozane PNU-22394 Ro60-0175 Ro60-0213 Vabicaserin WAY-629 WAY-161,503 YM-348 Antagonists : Atypical antipsychotics : Clorotepine Clozapine Iloperidone Melperone Olanzapine Paliperidone Pimozide Quetiapine Risperidone Sertindole Ziprasidone Zotepine ; Typical antipsychotics : Chlorpromazine Loxapine Pipamperone ; Antidepressants : Agomelatine Amitriptyline Amoxapine Aptazapine Etoperidone Fluoxetine Mianserin Mirtazapine Nefazodone Nortriptyline Tedatioxetine Trazodone ; Others : Adatanserin CEPC Cinanserin Cyproheptadine Deramciclane Dotarizine Eltoprazine Esmirtazapine FR-260,010 Ketanserin Ketotifen Latrepirdine Metitepine/Methiothepin Methysergide Pizotifen Ritanserin RS-102,221 S-14,671 SB-200,646 SB-206,553 SB-221,284 SB-228,357 SB-242,084 SB-243,213 SDZ SER-082 Xylamidine
Agonists : Lysergamides : Dihydroergotamine Ergotamine Lisuride LSD Mesulergine Metergoline Methysergide ; Tryptamines : 2-Methyl-5-HT 5-BT 5-CT 5-MT Bufotenin E-6801 E-6837 EMD-386,088 EMDT LY-586,713 N -Methyl-5-HTTryptamine ; Others : WAY-181,187 WAY-208,466 Antagonists : Antidepressants : Amitriptyline Amoxapine Clomipramine Doxepin Mianserin Nortriptyline ; Atypical antipsychotics : Aripiprazole Asenapine Clorotepine Clozapine Fluperlapine Iloperidone Olanzapine Tiospirone ; Typical antipsychotics : Chlorpromazine Loxapine ; Others : BGC20-760 BVT-5182 BVT-74316 Cerlapirdine EGIS-12,233 GW-742,457 Ketanserin Latrepirdine Lu AE58054 Metitepine/Methiothepin MS-245 PRX-07034 Ritanserin Ro04-6790 Ro 63-0563 SB-258,585 SB-271,046 SB-357,134 SB-399,885 SB-742,457
Agonists : Lysergamides : LSD ; Tryptamines : 5-CT 5-MT Bufotenin ; Others : 8-OH-DPAT AS-19 Bifeprunox E-55888 LP-12 LP-44 RU-24,969 Sarizotan Antagonists : Lysergamides : 2-Bromo-LSD Bromocriptine Dihydroergotamine Ergotamine Mesulergine Metergoline Methysergide ; Antidepressants : Amitriptyline Amoxapine Clomipramine Imipramine Maprotiline Mianserin ; Atypical antipsychotics : Amisulpride Aripiprazole Clorotepine Clozapine Olanzapine Risperidone Sertindole Tiospirone Ziprasidone Zotepine ; Typical antipsychotics : Chlorpromazine Loxapine ; Others : Butaclamol EGIS-12,233 Ketanserin LY-215,840 Metitepine/Methiothepin Pimozide Ritanserin SB-258,719 SB-258,741 SB-269,970 SB-656,104 SB-656,104-A SB-691,673 SLV-313 SLV-314 Spiperone SSR-181,507 Vortioxetine
Macromerine »
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"Macromerine ".
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