Pyrazolopyridine

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Pyrazolo[3,4-b]pyridine, the base chemical structure of this class.

The pyrazolopyridines are a chemical class of anxiolytic drugs which act as positive allosteric modulators of the GABAA receptor at the barbiturate binding site.12 They include the following compounds:

See also

References

  1. ^ Annual Reports in Medicinal Chemistry: Volume 16. Amsterdam: Elsevier. 1981. ISBN 0-12-040516-4. 
  2. ^ Progress in Drug Research / Volume 31 (Progress in Drug Research). Boston: Birkhauser. 1987. ISBN 3-7643-1837-6. 
GABAA
PAMs
non-N05B
Pyrazolopyridines
α2δ VDCC Blockers
5-HT1A Agonists
H1 Antagonists
CRH1 Antagonists
NK2 Antagonists
MCH1 antagonists
mGluR2/3 Agonists
mGluR5 NAMs
TSPO agonists
σ1 agonists
Others

M: PSO/PSI

dsrd (o, p, m, p, a, d, s), sysi/epon, spvo

proc (eval/thrp), drug (N5A/5B/5C/6A/6B/6D)


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